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<h1 class="title">Bilan semaine 25 2025 : 16 juin - 20 juin</h1>
<div class="quarto-categories">
<div class="quarto-category">colBiSBM</div>
<div class="quarto-category">inférence</div>
<div class="quarto-category">GNN</div>
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</div>
<div class="quarto-title-meta-author">
<div class="quarto-title-meta-heading">Auteur·rice</div>
<div class="quarto-title-meta-heading">Affiliation</div>
<div class="quarto-title-meta-contents">
<p class="author">Louis Lacoste <a href="mailto:louis.lacoste@agroparistech.fr" class="quarto-title-author-email"><i class="bi bi-envelope"></i></a> <a href="https://orcid.org/0009-0004-0178-9821" class="quarto-title-author-orcid"> <img src="data:image/png;base64,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"></a></p>
</div>
<div class="quarto-title-meta-contents">
<p class="affiliation">
MIA Paris-Saclay, INRAE, AgroParisTech, Université Paris-Saclay
</p>
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</div>
<div class="quarto-title-meta">
<div>
<div class="quarto-title-meta-heading">Date de publication</div>
<div class="quarto-title-meta-contents">
<p class="date">20 juin 2025</p>
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</div>
<div>
<div class="quarto-title-meta-heading">Modifié</div>
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<p class="date-modified">22 octobre 2025</p>
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<h2 id="toc-title">Sur cette page</h2>
<ul>
<li><a href="#todo-list" id="toc-todo-list" class="nav-link active" data-scroll-target="#todo-list">TODO List</a>
<ul class="collapse">
<li><a href="#inférence-et-microbes" id="toc-inférence-et-microbes" class="nav-link" data-scroll-target="#inférence-et-microbes">Inférence et microbes</a></li>
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<li><a href="#lecture-en-cours" id="toc-lecture-en-cours" class="nav-link" data-scroll-target="#lecture-en-cours">Lecture en cours</a>
<ul class="collapse">
<li><a href="#ot" id="toc-ot" class="nav-link" data-scroll-target="#ot">OT</a></li>
<li><a href="#inférence-de-graphes" id="toc-inférence-de-graphes" class="nav-link" data-scroll-target="#inférence-de-graphes">Inférence de graphes</a></li>
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<li><a href="#a-discuter" id="toc-a-discuter" class="nav-link" data-scroll-target="#a-discuter">A discuter</a>
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<li><a href="#inférence" id="toc-inférence" class="nav-link" data-scroll-target="#inférence">Inférence</a></li>
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<section id="todo-list" class="level2">
<h2 class="anchored" data-anchor-id="todo-list">TODO List</h2>
<ul>
<li><p>Pour clustering de collections sur données réelles :<br>
→ Lintuition de Pierre semble être confirmé, les dissimilarités semblent arrêter de varier sensiblement pour de grandes valeurs <span class="math inline">(Q_1,Q_2)</span>.</p>
<ul>
<li>✅ Si plusieurs clustering possibles les tester et sélectionner le meilleur</li>
<li>✅ Ré-ajuster les bonnes partitions.</li>
<li>❓Je narrive plus à reproduire le bug pour linférence…</li>
</ul></li>
<li><p><strong>Oui cest bien le cas</strong> Clustering descendant &amp; ascendant : vérifier quau cours du temps le <span class="math inline">BICL_{asc} \geq BICL_{desc}</span></p></li>
<li><p>Creuser et explorer avec easy16s !</p></li>
<li><p>✅ Comparer les perfs du VAE sur Baldock avec colBiSBM par exemple</p></li>
</ul>
<table>
<caption>
AUC values for colBiSBM and VGAE models across cities
</caption>
<thead>
<tr>
<th style="empty-cells: hide;border-bottom:hidden;" colspan="1">
</th>
<th style="border-bottom:hidden;padding-bottom:0; padding-left:3px;padding-right:3px;text-align: center; " colspan="2">
<div style="border-bottom: 1px solid #ddd; padding-bottom: 5px; ">
AUC
</div>
</th>
</tr>
<tr>
<th style="text-align:left;">
City
</th>
<th style="text-align:right;">
colBiSBM
</th>
<th style="text-align:right;">
Untuned VGAE
</th>
</tr>
</thead>
<tbody>
<tr>
<td style="text-align:left;">
Bristol
</td>
<td style="text-align:right;">
0.798
</td>
<td style="text-align:right;">
0.755
</td>
</tr>
<tr>
<td style="text-align:left;">
Edinburgh
</td>
<td style="text-align:right;">
0.836
</td>
<td style="text-align:right;">
0.774
</td>
</tr>
<tr>
<td style="text-align:left;">
Leeds
</td>
<td style="text-align:right;">
0.854
</td>
<td style="text-align:right;">
0.760
</td>
</tr>
<tr>
<td style="text-align:left;">
Reading
</td>
<td style="text-align:right;">
0.867
</td>
<td style="text-align:right;">
0.740
</td>
</tr>
</tbody>
</table>
<ul>
<li><p>Dé-bugger les simulations :</p>
<ul>
<li>⌛ Inférence : Relancer simus dinférence avec n = 240 pour voir si la qualité augmenter (se rassurer). En fait on est déjà à 240, jai relancé avec M = 4 au lieu de M = 2. En attente résultats MIGALE -&gt; BUG, dois creuser mais juste des problèmes techniques -&gt; Visiblement il y a dautres problèmes que juste le plan de parallélisation.
<ul>
<li><strong>Non ça na pas lair dêtre ça</strong>. Vérifier si problème de version tidyverse pour vapply sur l<strong>inférence</strong>.</li>
<li>⌛Bon le bug ne se reproduit plus… les jobs sont juste trop longs (&gt; 120h) jai relancé, il ne reste que 182/972 conditions.</li>
</ul></li>
</ul></li>
<li><p><strong>Il suffisait de faire la màj soit même…</strong> Si problème de parallélisation vient de pb de version <em>future.callr</em> le signaler à MIGALE.</p></li>
<li><p>Kmeans sur la densité des réseaux subdoré pour pré-partitionner et <em>clusteriser</em>. Car densités déséquilibrées.</p></li>
</ul>
<div id="ref-kmeans-vae" class="quarto-float quarto-figure quarto-figure-center anchored">
<figure class="quarto-float quarto-float-ref figure">
<div aria-describedby="ref-kmeans-vae-caption-0ceaefa1-69ba-4598-a22c-09a6ac19f8ca">
<ul>
<li>Faire GNN-VAE Doré et sub-Doré avec kmeans et clustering sur lespace latent Jai commencé à regarder un peu</li>
</ul>
</div>
<figcaption class="quarto-float-caption-bottom quarto-float-caption quarto-float-ref quarto-uncaptioned" id="ref-kmeans-vae-caption-0ceaefa1-69ba-4598-a22c-09a6ac19f8ca">
Reference&nbsp;1
</figcaption>
</figure>
</div>
<section id="inférence-et-microbes" class="level3">
<h3 class="anchored" data-anchor-id="inférence-et-microbes">Inférence et microbes</h3>
<ul>
<li>Lancer <em>colBiSBM</em> sur <span class="math inline">OTU\times Sample</span> → problème du chargement en mémoire des données à voir</li>
<li>Lancer <em>colSBM</em> sur <span class="math inline">OTU\times OTU</span></li>
<li>Creuser <a href="https://raw.githubusercontent.com/cregouby/R-toulouse-tabnet/main/Tabnet_RR2023_fr_pdf.pdf">TabNet</a> de Christophe Regouby et les <a href="https://github.com/cregouby/Tutoriel_torch">exercices</a></li>
<li>Regarder <strong>SPARTA</strong> Rennes</li>
<li>Lire Papiers compositional data (Aitchison et al.&nbsp;intro)</li>
<li>Lire article multi-niveaux Saint-Clair</li>
<li>Demander à JA si elle connaît des réseaux dinteractions connus par les experts (idée dintégrer une connaissance experte et de voir les différences de structure par rapport à celle attendue)</li>
<li>Ecrire et étudier les modèles pour différents niveaux taxonomiques. <span class="math display">\begin{align*}
i \rightarrow &amp;~N^1_i \subseteq N^2_i \subseteq N^3_i &amp; \text{Taxonomie}\\
Z^0_i \overset{?}{=} &amp; Z^1_i \overset{?}{=} Z^2_i \overset{?}{=} Z^3_i &amp; \text{Groupes fonctionnels}
\end{align*}</span></li>
</ul>
</section>
</section>
<section id="lecture-en-cours" class="level2">
<h2 class="anchored" data-anchor-id="lecture-en-cours">Lecture en cours</h2>
<section id="ot" class="level3">
<h3 class="anchored" data-anchor-id="ot">OT</h3>
<ul>
<li><span class="citation" data-cites="mazeletUnsupervisedLearningOptimal">Mazelet, Flamary, et Thirion (<a href="#ref-mazeletUnsupervisedLearningOptimal" role="doc-biblioref">s.&nbsp;d.</a>)</span> Intéressant pour le transport optimal entre graphes de tailles différentes</li>
<li><span class="citation" data-cites="nennaLecture2Entropic">Nenna (<a href="#ref-nennaLecture2Entropic" role="doc-biblioref">s.&nbsp;d.b</a>)</span> Pour comprendre le problème dOT régularisé pour lentropie.</li>
<li><span class="citation" data-cites="nennaLecture1Monge">Nenna (<a href="#ref-nennaLecture1Monge" role="doc-biblioref">s.&nbsp;d.a</a>)</span></li>
</ul>
</section>
<section id="inférence-de-graphes" class="level3">
<h3 class="anchored" data-anchor-id="inférence-de-graphes">Inférence de graphes</h3>
<ul>
<li><span class="citation" data-cites="matchadoNetworkAnalysisMethods2021b">Matchado et al. (<a href="#ref-matchadoNetworkAnalysisMethods2021b" role="doc-biblioref">2021</a>)</span> ➡️ Nos données étant compositionnelles il faut utiliser:
<ul>
<li>CCLasso et SparCC</li>
<li>HARMONIES pour zéro inflation (Binomiale négative), COZINE centered log ratio transformation compositionnalité, zéro inflation et forte précision</li>
<li>MixMPLN pour générer K réseaux issus de K Poisson log Normal</li>
<li>mLDM peut enlever les arêtes indirectes.</li>
</ul></li>
<li>NetComi agrège plusieurs méthodes tout en permettant lanalyse différentielle !</li>
</ul>
<p>Si pas compositionnelles :</p>
<ul>
<li>Meta-Network pour arêtes indirectes et non linéaires</li>
<li>Environmentally-Driven Edge detection pour corriger les effets de lenvironnement</li>
</ul>
</section>
</section>
<section id="a-discuter" class="level2">
<h2 class="anchored" data-anchor-id="a-discuter">A discuter</h2>
<section id="inférence" class="level3">
<h3 class="anchored" data-anchor-id="inférence">Inférence</h3>
<ul>
<li>pbs : variance, bcp de zero, covariables, offset et taxonomie (Reseaux arretes differents niveaux : Genre, OTU …)</li>
</ul>
<blockquote class="blockquote">
<p>Combine networks at different taxonomic levels</p>
</blockquote>
<ul>
<li>Inférence + GREMLINS</li>
</ul>
</section>
</section>
<div id="quarto-appendix" class="default"><section class="quarto-appendix-contents" role="doc-bibliography" id="quarto-bibliography"><h2 class="anchored quarto-appendix-heading">Les références</h2><div id="refs" class="references csl-bib-body hanging-indent" data-entry-spacing="0" role="list">
<div id="ref-matchadoNetworkAnalysisMethods2021b" class="csl-entry" role="listitem">
Matchado, Monica Steffi, Michael Lauber, Sandra Reitmeier, Tim Kacprowski, Jan Baumbach, Dirk Haller, et Markus List. 2021. <span>«&nbsp;Network Analysis Methods for Studying Microbial Communities: <span>A</span> Mini Review&nbsp;»</span>. <em>Computational and Structural Biotechnology Journal</em> 19 (janvier): 268798. <a href="https://doi.org/10.1016/j.csbj.2021.05.001">https://doi.org/10.1016/j.csbj.2021.05.001</a>.
</div>
<div id="ref-mazeletUnsupervisedLearningOptimal" class="csl-entry" role="listitem">
Mazelet, Sonia, Rémi Flamary, et Bertrand Thirion. s.&nbsp;d. <span>«&nbsp;Unsupervised <span>Learning</span> for <span>Optimal Transport</span> Plan Prediction Between Unbalanced Graphs&nbsp;»</span>.
</div>
<div id="ref-nennaLecture1Monge" class="csl-entry" role="listitem">
Nenna, Luca. s.&nbsp;d.a. <span>«&nbsp;Lecture 1 <span>Monge</span> and <span>Kantorovich</span> Problems: From Primal to Dual&nbsp;»</span>.
</div>
<div id="ref-nennaLecture2Entropic" class="csl-entry" role="listitem">
———. s.&nbsp;d.b. <span>«&nbsp;Lecture 2: <span>Entropic Optimal Transport</span>&nbsp;»</span>.
</div>
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